Cic edizioni internazionali
Il Giornale di Chirurgia

Role of specimen US for predicting resection margin status in breast conserving therapy

Original Article, 201 - 204
doi: 10.11138/gchir/2015.36.5.201
Tag this article
Abstract
Enhanced HTML Full text PDF
Aim. To assess the diagnostic accuracy of specimen ultrasound (US) for predicting resection margin status in women undergoing breast conserving therapy for US-detected cancer, having the histological findings as the reference standard.
Patients and methods. A total of 132 consecutive patients (age range, 34-87 years; mean, 51 years) underwent breast-conserving surgery for US-detected invasive breast cancer. All surgical specimens underwent US examination. The presence of lesion within the specimen and its distance from the specimen margins were assessed considering a threshold distance between the lesion and specimen margins of 10 mm. US findings were then compared with the pathological ones and specimen US. Sensitivity, specificity, diagnostic accuracy, positive (PPV) and negative predictive values (NPV) for predicting histological margin status were evaluated, having the histological findings as the reference standard.
Results. The histological examination detected invasive ductal carcinoma in 96/132 (73%) cases, invasive lobular carcinoma in 32/132 (24%), mucinous carcinoma in 4/132 (3%). The pathological margin analysis revealed 96/132 (73%) negative margins and 36 (27%) close/positive margins. US examination detected all 132 breast lesions within the surgical specimens. 110 (83%) negative margins and 22 (17%) positive margins were found on US. Sensitivity, specificity, diagnostic accuracy, PPV and NPV of 44%, 94%, 80%, 73% and 82%, respectively, were found for specimen US.
Conclusions. Specimen US represents a time and cost saving imaging tool for evaluating the presence of US detected-breast lesion within surgical specimen and for predicting the histological margin status.

Vol. XXXIX (No. 2) 2018 March-April

  1. Does the Internet provide patients or clinicians with useful information regarding faecal incontinence? An observational study
    Leo C.A., Murphy J., Hodgkinson J.D., Vaizey C.J., Maeda Y.
    doi: 11138/gchir/2018.39.2.071
  2. The use of local anesthesia to perform lower limb revascularization in the fragile patient with critical limb ischemia
    Kontopodis N., Papaioannou A., Tavlas E., Papadopoulos G., Lioudaki S., Tzirakis K., Ioannou C.V.
    doi: 11138/gchir/2018.39.2.077
  3. Totally laparoscopic resection and extraction of specimens via transanal route in synchronous colon and gastric cancer
    Sumer F., Karakas S., Gundogan E., Sahin T., Kayaalp C.
    doi: 11138/gchir/2018.39.2.082
  4. Laparoscopic cholecystectomy for acute cholecystitis: are intended operative approach, timing and outcome affected by BMI? A multicenter retrospective study
    Lauro A., Vaccari S., Cervellera M., Casella G., D'Andrea V., Di Matteo F.M., Panarese A., Santoro A., Cirocchi R., Tonini V.
    doi: 11138/gchir/2018.39.2.087
  5. Severe neurological complication following adjustable gastric banding
    Martines G., Musa N., Aquilino F., Capuano P.
    doi: 11138/gchir/2018.39.2.092
  6. Malakoplakia of the large intestine: an incidental extremely rare finding
    Koutserimpas C., Ioannidis A., Demonakou M., Siaperas P., Skarpas A., Velimezis G., Karanikas I.
    doi: 11138/gchir/2018.39.2.097
  7. Superior vena cava syndrome due to central port catheter thrombosis: a real life-threatening condition
    Lianos G.D., Hasemaki N., Tzima E., Vangelis G., Tselios A., Mpailis I., Lekkas E.
    doi: 11138/gchir/2018.39.2.101
  8. Primary abdominal wall endometriosis: presentation of rarely seen two cases
    Ferhatoglu M.F., Senol K.
    doi: 11138/gchir/2018.39.2.107
  9. A case of peduncolated Brunner's gland hamartoma
    Tornambè A., Tornambè G.
    doi: 11138/gchir/2018.39.2.111
  10. Paget’s disease of the male breast: case report and a point of view from actual literature
    Vergine M., Musella A., Gulotta E., Frusone F., De Luca A., Maceli F., Libia A., Benedetti Panici P., Monti M.
    doi: 11138/gchir/2018.39.2.114
Last Viewed articles: la lista degli ultimi x visitati.
  1. Role of specimen US for predicting resection margin status in breast conserving therapy
    Moschetta M., Telegrafo M., Introna T., Coi L., Rella L., Ranieri V., Cirilli A., Stabile Ianora A.A., Angelelli G.
    doi: 10.11138/gchir/2015.36.5.201
credits