Cic edizioni internazionali
Il Giornale di Chirurgia

Ruolo della linfoadenectomia nel trattamento del cancro gastrico: analisi retrospettiva monocentrica su 406 pazienti

Articolo, 91 - 94
Tag this article
Abstract
Full text PDF
Background: Several studies in the literature have investigated the surgical technique for gastric cancer treatment. Particularly the role of an extended lymphadenectomy is still controversial. Our study compared morbidity and mortality among patients that underwent lymphadenectomy D2 and D2 extended (D2+).
Patients and Methods: 406 patients underwent surgery for gastric cancer. A total gastrectomy or a gastric resection with lymphadenectomy D2 or D2+ (extended to stations 12a, 12b, 12p) were performed.
Results: 250 (62.8%) patients had advanced cancer at the moment of diagnosis (stages I-19.4%, II-17.8%, III-26.8%, IV-36%). 342 patients underwent curative surgery and among those D0/D1, D2, D2+ lymphadenectomies were respectively 3,6%, 37,9% and 58,5%. In D2 and D2+ lymphadenectomy the median survival was 54.2 (OS 47%) and 39.4 months (OS 44%) respectively. The 5-years overall survival by stages after D2 or D2+ was 66.7% and 77.8% in Stage I, 59.6% and 55.6% in S-II, 26.1% and 32.8% in S-III, 13.8% and 29.4% in S-IV (p=0.242). Morbidity and mortality were 16,6% and 7% in D2 group and 10.9% and 7% in D2+ group.
Conclusions: Our experience suggests that a D2 lymphadenectomy can be performed with a satisfactory outcome in term of survival and mortality. D2+ lymphadenectomy does not seem to increase mortality and morbidity; however there are no significant differences in term of survival between the two techniques (p = 0,355).

Vol. XLI (No. 1) 2020 January - February

  1. Laparoscopic Roux-en-Y gastric bypass in the treatment of obesity: evidence based update through randomized clinical trials and meta-analyses
    Morales-Maza J., Rodriguez-Quintero J.H., Sanchez-Morales G.E., Sanchez Garcia-Ramos E., Romero-Velez G., Aguilar-Frasco J.L., Pimienta-Ibarra A.S., Alvarez-Bautista F.E., Leon P., Hernandez-Acevedo J.D., Del Angel-Millan G., Sierra M.
  2. Retroperitoneal sarcomas: from diagnosis to treatment. Case series and review of the literature
    Mantas D., Garmpis N., Polychroni D., Garmpi A., Damaskos C., Liakea A., Sypsa G., Kouskos E.
  3. The discriminative properties of erythrocyte anisocytosis in patients with resectable malignant pancreatic masses compared with an age and gender matched control group
    Akturk O.M., Çakir M.
  4. Diagnostic and therapeutic role of laparoscopy in perforated peptic ulcer in the elderly patients
    Giordano A., Prosperi P., Alemanno G., Bergamini C., Bruscino A., Valeri A.
  5. The role of laparoscopic surgery in isolated adrenal metastasis: our personal experience
    Frattolillo G., Paradiso G., Scarano Catanzaro V., Giordano L., Avantifiori R., D'Ermo G., Letizia C., De Toma G.
  6. Advances in bioengineering of complex tissues: state of the art of mucosae decellularization protocols
    Rizzo M.I., Contardi C., Esposito M., Zama M.
  7. An analysis of missed cases with surgical emergencies admitted in non-surgical departments. Case series and а review of the literature
    Popivanov G., Cirocchi R., Popov G., Stefanovski P., Andonova R., Kjossev K., Tonchev P., Tabakov M., Penkov M., Ivanov P., Mutafchiyski V.
  8. The evolution of robotic arm-assisted arthroplasty in Greece
    Koutserimpas C., Dretakis K.
  9. Current role of open surgery in adrenal tumors
    Chiappini A., Frattolillo G., Paradiso G., De Gori A., Scarano Catanzaro V., Avantifiori R., Fiori E., De Toma G.
  10. Preoperative fasting - “nihil per os” a difficult myth to break down: a randomized controlled study
    Panebianco A., Laforgia R., Volpi A., Punzo C., Vacca G., Minafra M., Di Salvo M., Pezzolla A.
  11. Sentinel lymph node biopsy with intraoperative touch imprint cytology (TIC) in breast cancer: experience of a mild-volume center
    Marano A., Sodano B., Vitiello C., Martini A.M., Baldassarre F., Siciliano A., Iannaci G.
  12. Spontaneous transdiaphragmatic intercostal hernia: clinical considerations and management
    Lonardo M.T., Frezzotti F., Collalti M., Natili A., Metere A.
  13. Systemic immune response after open tension-free inguinal hernia repair under different anesthetic alternatives: a prospective comparative study
    Symeonidis D., Diamantis A., Baloyiannis I., Tzovaras G., Tepetes K.
  14. Minilaparotomic incision for haemorrhagic corpus luteum: a case report
    Leanza V., Mininni C., Di Grazia F.M., Genovese F., Carbonaro A., Leanza G., Palumbo M.
  15. Conservative management of streptococcal necrotizing periorbital fasciitis following primary VZV infection
    Kontou E., Bontzos G., Triantafyllou D., Garnavou-Xirou C., Ragkousis A., Xirou T.
  16. Relief of hemorrhoid symptoms: pilot study of a new topical ally
    Gaj F., Bianchi F.P., Passannanti D., Tedesco D.
  17. Topical use of tranexamic acid in primary total knee arthroplasty: a comparative study
    Besiris G.TH., Koutserimpas C., Karamitros A., Karaiskos I., Tsakalou D., Raptis K., Kourelis K., Paxinos O., Kotsirakis A., Vlasis K.
  18. Insights in clinical examination and diagnosis of Athletic Pubalgia
    Koutserimpas C., Ioannidis A., Konstantinidis M.K., Makris M.C., Antonakopoulos F., Mazarakis A., Papagelopoulos P.J., Vlasis K., Konstantinidis M.K.
Last Viewed articles: la lista degli ultimi x visitati.
  1. Ruolo della linfoadenectomia nel trattamento del cancro gastrico: analisi retrospettiva monocentrica su 406 pazienti
    Vestri A., Canonico G., Scaringi S., Liscia G., Tonelli F.
credits