Intussusception is a rare condition in the adult population: it is responsible for 1% of all bowel obstructions.
In most of intussusceptions a malignant tumor is involved; a lot of studies show that approximately 50% of malignant metastases causing small bowel intussusception are metastatic melanomas.
In present paper a case of a small bowel intussusception probably due to metastases of an occult melanoma, in a 69-year-old patient, is presented.
Surgery resection, careful research of possible primitive neoplasms and an accurate follow-up program has been the treatment of choice.
All the investigations carried out did not allow to identify a possible primitive neoplasm.
The last whole body PET carried out 44 months after surgery resulted disease-free.
KEY WORDS: melanoma - Bowel Intussusception - Case report.