VOLUME 39 - NUMBER 3 - 2018

Thyroid neoplasms: surgical and cyto-histopathological connections on a six year cases study

  • Fontana T., Izzo M., Venturelli P., Lentini V.L., Falco N., Gulotta L., Florena A.M., Cocorullo G.
  • Original Article, 158-165
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  • Objective. This study aims to evaluate the percentage of cyto-histologic correlation in patients with a thyroid disease documented through clinical-instrumental, cytological (FNAB), histological and surgical examinations. The purpose of this study is also to determine the percentage of disease incidence and evaluating any surgical indication in relation to biological behavior (benign, malignant or indeterminate lesions, occult carcinomas), sex, and age.

    Background. Almost all of thyroid neoplasms is manifested through thyroid nodule. Therefore, clinical evidence of the thyroid nodule analysis is primarily related to the need to exclude malignant pathology or carcinoma of the thyroid, present in 4-6.5% of cases.

    Patients and methods. The trial was conducted analyzing the data including cytological and histology thyroid reports recorded from 1 March 2010 to 1 March 2016, for a total of 5,956 reports. To determine the cyto-histological correlations, have been considered eligible all patients of both sexes, that have performed at least one cytologic exam followed by an histologic exam. Thus, the total number of the cases studied is 554 cases.

    Results. Cyto-histologic compliance was 93% with a diagnostic accuracy of 4% higher than the literature examined.

    Conclusions. The results thus obtained show, furthermore, that there is a non-negligible percentage of thyroid disease with malignant biological behavior and involvement of male individuals. Therefore, the execution of the FNAB is of utmost importance for the purpose of a correct surgical indication.

  • KEY WORDS: thyroid - Bethesda - tIR - FnAB.