Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with an estimated worldwide incidence of 0.5-2 per million/year.
Complete surgical removal of ACC represents the current treatment of choice for this tumor.
A disease-free resection margin (R0) is an important predictor of long-term survival: surgery is demanding and must be performed by a highly experienced surgical team.
We report the surgical strategy adopted in a patient with locally advanced ACC and virilization to obtain a R0 resection.
KEY WORDS: Adrenal cancer - Endocrine - Laparotomy - Virilization.