VOLUME 36 - NUMBER 5 - 2015

Multi-organ resection for locally advanced adrenocortical cancer: surgical strategy and literature review


  • Guida F., Clemente M., Valvano L., Napolitano C.
  • Clinical practice, 225-230
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  • Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with an estimated worldwide incidence of 0.5-2 per million/year. Complete surgical removal of ACC represents the current treatment of choice for this tumor. A disease-free resection margin (R0) is an important predictor of long-term survival: surgery is demanding and must be performed by a highly experienced surgical team. We report the surgical strategy adopted in a patient with locally advanced ACC and virilization to obtain a R0 resection.

  • KEY WORDS: Adrenal cancer - Endocrine - Laparotomy - Virilization.