VOLUME 33 - NUMBER 1-2 - 2012

Lymphoepithelioma-like gastric carcinoma presenting as giant ulcer of the lesser curvature. Case report

  • , Pasteli N., Paraskevas G., Chatzopoulos S., Papadimitriou N., Kotronis A., Konstantara A., Makrantonakis A., Kakoutis E.
  • Clinical practice, 21-23
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  • Lymphoepithelioma-like gastric carcinoma (LELGC) has special clinicopathologic features that differentiate it from the common gastric adenocarcinoma. LELGC is a rare neoplasm of the stomach with an incidence of 1-4% of all gastric cancers and is characterized by desmoplastic stroma uniformaly infiltrated by abundant lymphocytes and plasma cells. LELGC is closely associated with the Epstein-Barr virus (EBV), with 80-100% of LELGC being EBV-positive. LELGC has a male predominance, occurs in elderly people and is usually located in the upper and middle portion of the stomach. We report a rare case of lymphoepithelioma-like gastric carcinoma located in the lesser curvature at the border of the gastric body to the pyloric antrum.

  • KEY WORDS: Stomach - Carcinoma - Lymphoepitelioma - Ulcer.