VOLUME 32 - NUMBER 8-9 - 2011

An unusual case of hepatic carcinosarcoma

  • Lai Q., Levi Sandri G.B., Melandro F., Di Laudo M., Garofalo M., Guglielmo N., Grieco M., Di Tondo U., Rossi M., Berloco P.B.
  • Clinical practice, 372-373
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  • We report a rare case of a hepatic carcinosarcoma with rabdomyosarcomatous differentiation in its sarcomatous component. A 71-year old Caucasian female patient underwent a liver resection for a 4-cm lesion developed on an underlying HCV-related cirrhosis. Post-operative course was uneventful and the patient was discharged 5 days after surgery. At pathology, the tumor presented the features of hepatocellular carcinoma and rhabdomyosarcoma Three months later the patient experienced a liver recurrence, dying 2 months later for systemic disease. The reported case presents several peculiarities, i.e. the female gender, the HCV-related cirrhotic status, and the European origin of the patient. However, the outcome of our case confirms that this neoplasm pursues a highly aggressive course with poor prognosis.

  • KEY WORDS: Hepatocellular carcinoma - Carcinosarcoma - Surgery.