VOLUME 29 - NUMBER 8-9 - 2008

Involvement of electrophysiological localization of the subthalamic nucleus in deep brain stimulation for Parkinson’s disease


  • Ulivieri S., Nguyen J.P., Keravel Y., Mencattini G., Lefaucheur J.P., Mohsen N.
  • Articolo Originale, 335-338
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  • Versione Italiana: Abbiamo analizzato il ruolo della localizzazione elettrofisiologica del nucleo subtalamico (NST), utilizzando un sistema di registrazione multi-unitaria con semielettrodi in un gruppo di trenta pazienti affetti da malattia di Parkinson sottoposti a stimolazione cerebrale profonda del NST sotto anestesia sia locale che generale, valutando i risultati ottenuti e confrontandoli con i dati presenti in letteratura.

    English version: We studied the involvement of the electrophysiological localization of the subthalamic nucleus (NST) using a multi-unit recording technique by means of semi-microelectrode in a set of thirty Parkinson’s patients who benefited from a bilateral stimulation of the NST and who were operated on under local or general anesthesia. The multi-unit recording technique by means of semi-microelectrodes appeared efficient, capable of improving the localization of the NST and leading to improvement in clinical results. We believe that the use of our technique will allow for time savings while providing good results, and that the choice of the angle of the trajectory will allow for improved localization of the NST and thus improved clinical results.

  • KEY WORDS: Subtalamo - Stimolazione cerebrale profonda - Malattia di Parkinson. Subthalamus - Deep brain stimulation - Parkinson’s disease.