Cic edizioni internazionali
Il Giornale di Chirurgia

Role of specimen US for predicting resection margin status in breast conserving therapy

Original Article, 201 - 204
doi: 10.11138/gchir/2015.36.5.201
Tag this article
Abstract
Enhanced HTML Full text PDF
Aim. To assess the diagnostic accuracy of specimen ultrasound (US) for predicting resection margin status in women undergoing breast conserving therapy for US-detected cancer, having the histological findings as the reference standard.
Patients and methods. A total of 132 consecutive patients (age range, 34-87 years; mean, 51 years) underwent breast-conserving surgery for US-detected invasive breast cancer. All surgical specimens underwent US examination. The presence of lesion within the specimen and its distance from the specimen margins were assessed considering a threshold distance between the lesion and specimen margins of 10 mm. US findings were then compared with the pathological ones and specimen US. Sensitivity, specificity, diagnostic accuracy, positive (PPV) and negative predictive values (NPV) for predicting histological margin status were evaluated, having the histological findings as the reference standard.
Results. The histological examination detected invasive ductal carcinoma in 96/132 (73%) cases, invasive lobular carcinoma in 32/132 (24%), mucinous carcinoma in 4/132 (3%). The pathological margin analysis revealed 96/132 (73%) negative margins and 36 (27%) close/positive margins. US examination detected all 132 breast lesions within the surgical specimens. 110 (83%) negative margins and 22 (17%) positive margins were found on US. Sensitivity, specificity, diagnostic accuracy, PPV and NPV of 44%, 94%, 80%, 73% and 82%, respectively, were found for specimen US.
Conclusions. Specimen US represents a time and cost saving imaging tool for evaluating the presence of US detected-breast lesion within surgical specimen and for predicting the histological margin status.

Vol. XXXVIII (No. 1) 2017 January - February

  1. The non-surgical management for hemorrhoidal disease. A systematic review
    Cocorullo G., Tutino R., Falco N., Licari L., Orlando G., Fontana T., Raspanti C., Salamone G., Scerrino G., Gallo G., Trompetto M., Gulotta G.
    doi: 10.11138/gchir/2017.38.1.005
  2. 23-hour observation endocrine neck surgery: lessons learned from a case series of over 1700 patients
    Raspanti C., Porrello C., Augello G., Dafnomili A., Rotolo G., Randazzo A., Falco N., Fontana T., Tutino R., Gulotta G.
    doi: 10.11138/gchir/2017.38.1.015
  3. Lymph node assessment in colorectal cancer surgery: laparoscopic versus open techniques
    Balducci G., Sederino M.G., Laforgia R., Carbotta G., Minafra M., Delvecchio A., Fedele S., Tromba A., Carbone F., Palasciano N.
    doi: 10.11138/gchir/2017.38.1.023
  4. Caecal leiomyoma detected by whole-body MRI in a patient with Hodgkin lymphoma: first case report
    Albano D., Sinagra E., Patti C., Narese D., Agrusa A., Di Buono G., Raimondo D., Midiri M., Lagalla R., Galia M.
    doi: 10.11138/gchir/2017.38.1.027
  5. Deep sternal wound infections: a severe complication after cardiac surgery
    Morgante A., Romeo F.
    doi: 10.11138/gchir/2017.38.1.033
  6. Neoplastic sigmoid-uterine fistula. An exceptional complication of large intestine cancer
    Zanghì G., Leanza V., Vecchio R., D'Agati A., Cordova S., Rinzivillo N.M., Lodato M., Leanza G.
    doi: 10.11138/gchir/2017.38.1.037
  7. Deep SSI after mesh-mediated groin hernia repair: management and outcome in an Emergency Surgery Department
    Salamone G., Licari L., Augello G., Campanella S., Falco N., Tutino R., Cocorullo G., Gullo R., Raspanti C., De Marco P., Porrello C., Profita G., Gulotta G.
    doi: 10.11138/gchir/2017.38.1.041
  8. Agenesis of the internal carotid artery: a family pathology?
    Perla F.M., Carbotta G., Di Nardo D., D'Avanzo M., Colaiacomo M.C., Di Biasi C., Falvo L., Carbotta S., Maturo A., Tartaglia F., Tromba L.
    doi: 10.11138/gchir/2017.38.1.046
  9. Cyanoacrylate sealant compared to fibrin glue in staple line reinforcement during laparoscopic sleeve gastrectomy. Pilot prospective observational study
    Martines G., Digennaro R., De Fazio M., Capuano P.
    doi: 10.11138/gchir/2017.38.1.050
  10. Supergiant fecaloma as manifestation of chronic constipation
    Currò G., Lazzara C., Latteri S., Bartolotta M., Navarra G.
    doi: 10.11138/gchir/2017.38.1.053
Last Viewed articles: la lista degli ultimi x visitati.
  1. Role of specimen US for predicting resection margin status in breast conserving therapy
    Moschetta M., Telegrafo M., Introna T., Coi L., Rella L., Ranieri V., Cirilli A., Stabile Ianora A.A., Angelelli G.
    doi: 10.11138/gchir/2015.36.5.201
credits